Some Details About IgA Nephropathy

IgA nephropathy is seen commonly in our daily life, but most of people don't know what it is. the following introduces some details about IgA nephropathy, we hope a part of passage may help you greatly.
Nephropathy is damage disease, or other problems with the kidney. IgA nephropathy is a kidney disorder in which antibodies called IgA build up in kidney tissue.It is also called Berger's disease.
Causes
IgA is a protein called an antibody that helps the body fight infections. IgA nephropathy (Berger's disease) occurs when too much of this protein is deposited in the kidneys. IgA builds up inside the small blood vessels of the kidney. Structures in the kidney called glomeruli become inflamed and damaged.
IgA nephropathy (Berger's disease) is a form of mesangial proliferative nephritis.
The disorder can appear suddenly (acute), or get worse slowly over many years (chronic glomerulonephritis).
Risk factors include:
A personal or family history of IgA nephropathy or Henoch Schonlein purpura, a form of vasculitis that affects many parts of the body
Caucasian or Asian ethnicity
IgA nephropathy can occur in people of all ages, but it most often affects males in their teens to late 30s.
Symptoms
There may be no symptoms for many years.
Symptoms include:
Bloody urine that starts during or soon after a respiratory infection
Repeated episodes of dark or bloody urine
Swelling of the hands and feet
Symptoms of chronic kidney disease
Treatment
The goal of treatment is to relieve symptoms and prevent or delaychronic renal failure.
You may get medicines to control high blood pressure and swelling (edema), such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). Controlling blood pressure is the most important way to delay kidney damage.
Corticosteroids, other drugs that suppress the immune system, and fish oil have also been used to treat this disorder.
Salt and fluids may be restricted to control swelling. A low to moderate protein diet may be recommended in some cases.
Some people will need to take medicines to lower their cholesterol.
Eventually, many patients must be treated for chronic kidney disease and may need dialysis.
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